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Mechanism of Action: Valacyclovir is a nucleoside analogue DNA polymerase inhibitor.
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Uno studio di farmacocinetica con somministrazione di dosi multiple, condotto in soggetti con cirrosi epatica lieve e non progressiva ha dimostrato un aumento dell’emivita plasmatica del farmaco e una AUC e una C maxcorrispondenti a circa tre volte i valori riscontrati nei soggetti normali?
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